Giovana Tardin Torrezan
Pesquisadora Científica no Grupo de Genômica e Biologia Molecular do Centro Internacional de Pesquisa - A. C.Camargo Cancer Center e orientadora do Programa de Pós Graduação em Oncologia da Fundação Antônio Prudente. Atuou como Gerente Científica em laboratório privado com foco na área de testes moleculares em Oncologia.
Formação
Graduação Ciências Biológicas pela Universidade Federal do Paraná (UFPR), mestrado em Genética pelo Programa de Pós-Graduação em Genética da Universidade Federal do Paraná (UFPR) e doutorado em Oncologia pela Fundação Antônio Prudente - A.C.Camargo Cancer Center (2014), com período de sanduíche no MD Anderson Cancer Center.
Contato
Telefone: (11) 2189-5000 - ramal: 2953
E-mail: [email protected]
- Genômica
- Biologia Molecular e Genética, com ênfase em Genética Humana e Oncogenética.
Ferrari A, Torrezan GT, Carraro DM, Aguiar Junior S. Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer. Nutrients. 2019 Jun 18;11(6). pii: E1368. doi: 10.3390/nu11061368. PubMed PMID: 31216671.
Ugolini-Lopes MR, Torrezan GT, Gândara APR, Olivieri EHR, Nascimento IS, Okazaki E, Bonfá E, Carraro DM, de Andrade DCO. Enhanced type I interferon gene signature in primary antiphospholipid syndrome: Association with earlier disease onset and preeclampsia. Autoimmun Rev. 2019 Apr;18(4):393-398. doi:10.1016/j.autrev.2018.11.004. Epub 2019 Feb 14. PubMed PMID: 30772492.
Cotrim DP, Ribeiro ARG, Paixão D, de Queiroz Soares DC, Jbili R, Pandolfi NC, Cezana C, de Cássia Mauro C, Mantoan H, Bovolim G, de Brot L, Torrezan GT, Carraro DM, Baiocchi G, da Cruz Formiga MN, da Costa AABA. Prevalence of BRCA1 and BRCA2 pathogenic and likely pathogenic variants in non-selected ovarian carcinoma patients in Brazil. BMC Cancer. 2019 Jan 3;19(1):4. doi: 10.1186/s12885-018-5235-3. PubMed PMID: 30606148; PubMed Central PMCID: PMC6319008.
Liberman PHP, Goffi-Gomez MVS, Schultz C, Jacob PL, de Paula CAA, Sartorato EL, Torrezan GT, Ferreira EN, Carraro DM. Contribution of the GSTP1 c.313A>G variant to hearing loss risk in patients exposed to platin chemotherapy during childhood. Clin Transl Oncol. 2019 May;21(5):630-635. doi:10.1007/s12094-018-1964-7. Epub 2018 Oct 25. PubMed PMID: 30361796.
Vaccaro CA, López-Kostner F, Adriana DV, Palmero EI, Rossi BM, Antelo M, Solano A, Carraro DM, Forones NM, Bohorquez M, Lino-Silva LS, Buleje J, Spirandelli F, Abe-Sandes K, Nascimento I, Sullcahuaman Y, Sarroca C, Gonzalez ML, Herrando AI, Alvarez K, Neffa F, Galvão HC, Esperon P, Golubicki M, Cisterna D, Cardoso FC, Torrezan GT, Junior SA, Pimenta CAM, da Cruz Formiga MN, Santos E, Sá CU, Oliveira EP, Fujita R, Spirandelli E, Jimenez G, Guindalini RSC, de Azevedo RGMV, Bueno LSM, Dos Santos Nogueira ST, Loarte MT, Padron J, Del Carmen Castro-Mujica M, Del Monte JS, Caballero C, Peña CMM, Pinto J, Barletta-Carrillo C, Melva GA, Piñero T, Beltran PM, Ashton-Prolla P, Rodriguez Y, Quispe R, Rossi NT, Martin C, Chialina S, Kalfayan PG, Bazo-Alvarez JC, Cañete AR, Dominguez-Barrera C, Nuñez L, Da Silva SD, Balavarca Y, Wernhoff P, Plazzer JP, Møller P, Hovig E, Dominguez-Valentin M; in collaboration with GETH. From colorectal cancer pattern to the characterization of individuals at risk: Picture for genetic research in Latin America. Int J Cancer. 2019 Jul 15;145(2):318-326. doi: 10.1002/ijc.31920. Epub 2018 Dec 5. Review. PubMed PMID: 30303536; PubMed Central PMCID: PMC6587543.
da Cunha IW, da Costa WH, Morini MA, Bezerra SM, Carraro DM, Torrezan GT, Formiga MNC, Guimaraes GC, Zequi SC, Soares FA. Expanding morphological and clinical aspects of hereditary leiomyomatosis and renal cell carcinoma (HLRCC): a case report in a patient with unusual morphology and clinical presentation. Virchows Arch. 2018 Dec;473(6):775-779. doi: 10.1007/s00428-018-2420-3. Epub 2018 Aug 31. PubMed PMID: 30171332.
de Figueiredo Barros BD, Kupper BEC, Aguiar Junior S, de Mello CAL, Begnami MD, Chojniak R, de Souza SJ, Torrezan GT, Carraro DM. Mutation Detection in Tumor-Derived Cell Free DNA Anticipates Progression in a Patient With Metastatic Colorectal Cancer. Front Oncol. 2018 Aug 10;8:306. doi: 10.3389/fonc.2018.00306. eCollection 2018. PubMed PMID: 30148116; PubMed Central PMCID: PMC6095987.
Torrezan GT, de Almeida FGDSR, Figueiredo MCP, Barros BDF, de Paula CAA, Valieris R, de Souza JES, Ramalho RF, da Silva FCC, Ferreira EN, de Nóbrega AF, Felicio PS, Achatz MI, de Souza SJ, Palmero EI, Carraro DM. Complex Landscape of Germline Variants in Brazilian Patients With Hereditary and Early Onset Breast Cancer. Front Genet. 2018 May 7;9:161. doi: 10.3389/fgene.2018.00161. eCollection 2018. PubMed PMID: 29868112; PubMed Central PMCID: PMC5949367.
Silva FC, Torrezan GT, Brianese RC, Stabellini R, Carraro DM. Pitfalls in genetic testing: a case of a SNP in primer-annealing region leading to allele dropout in BRCA1. Mol Genet Genomic Med. 2017 May 11;5(4):443-447. doi: 10.1002/mgg3.295. eCollection 2017 Jul. PubMed PMID: 28717669; PubMed Central PMCID: PMC5511807.
Silva FCC, Torrezan GT, Ferreira JRO, Oliveira LP, Begnami MDFS, Aguiar S Junior, Carraro DM. Germline Mutations in MLH1 Leading to Isolated Loss of PMS2 Expression in Lynch Syndrome: Implications for Diagnostics in the Clinic. Am J Surg Pathol. 2017 Jun;41(6):861-864. doi: 10.1097/PAS.0000000000000827. PubMed PMID: 28248820.
Equipe
