Tiago Góss dos Santos
Pesquisador do Centro Internacional de Pesquisa (CIPE) e docente do Programa de Pós-Graduação em Oncologia da Fundação Antônio Prudente.
Formação
Bacharel em Ciências Biológicas pela Universidade Federal de Santa Catarina (2002), mestre em Neurociências pela Universidade Federal de Santa Catarina (2005), doutor em Oncologia pela Fundação Antônio Prudente (2009). Pós-doutorado no Instituto Ludwig de Pesquisa sobre o Câncer (2012).
Contato
Telefone: (11) 2189-5000 - ramal: 2943
E-mail: [email protected]
Clique aqui para conferir as publicações.
ROQUE-LIMA B, ROQUE CCTA, BEGNAMI MD, PERESI P, LIMA ENP, MELLO CAL, COIMBRA FJF, CHOJNIAK R, GOSS SANTOS T. Development of patient-derived orthotopic xenografts from metastatic colorectal cancer in nude mice. J. Drug Target. 2018 Sep 5:1-7
VECCHI L, ZOIA MAP, GOSS SANTOS T et al. Inhibition of the AnxA1/FPR1 autocrine axis reduces MDA-MB-231 breast cancer cell growth and aggressiveness in vitro and in vivo. Biochim Biophys Acta. 2018 0167-4889(18)30138-1.
SANTOS TG, MARTINS VR, HAJJ G. Unconventional Secretion of Heat Shock Proteins in Cancer. Int J Mol Sci. 18(5):E946, 2017.
IGLESIA RP, PRADO MB, CRUZ L, MARTINS VR, SANTOS TG, LOPES MH. Engagement of cellular prion protein with the co-chaperone Hsp70/90 organizing protein regulates the proliferation of glioblastoma stem-like cells. Stem Cell Res Ther. 17(1):76, 2017.
DE LACERDA TC, COSTA-SILVA B, GIUDICE FS, DIAS MV, DE OLIVEIRA GP, TEIXEIRA BL, SANTOS TG, MARTINS VR. Prion protein binding to HOP modulates the migration and invasion of colorectal cancer cells. Clin Exp Metastasis. 33:441-51, 2016.
MUÑOZ JJ, DRIGO SA, KUASNE H, VILLACIS RA, MARCHI FA, DOMINGUES MA, LOPES A, SANTOS TG, ROGATTO SR. A comprehensive characterization of cell cultures and xenografts derived from a human verrucous penile carcinoma. Tumour Biol. 37:11375-84, 2016.
SANTOS TG, LOPES MH, MARTINS VR. Targeting prion protein interactions in cancer. Prion 9:165-73, 2015.
LOPES MH*, SANTOS TG*, RODRIGUES BR, et al. Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival. Oncogene. 2014 Aug 25. doi: 10.1038/onc.2014.261. * autores contribuíram igualmente na publicação.
SANTOS TG et al. Laminin-γ1 chain and stress inducible protein 1 synergistically mediate PrPC-dependent axonal growth via Ca2+ mobilization in dorsal root ganglia neurons. Journal of Neurochemistry, v. 124, p.210-223, 2013.
SANTOS TG et al. Enhanced neural progenitor/stem cells self-renewal via the interaction of stress-inducible protein 1 with the prion protein. Stem Cells, 29(7):1126-36, 2011.
Equipe
